KEGG   Rattus norvegicus (rat): 297893
Entry
297893            CDS       T01003                                 
Symbol
Hdac1
Name
(RefSeq) histone deacetylase 1
  KO
K06067  histone deacetylase 1/2 [EC:3.5.1.98]
Organism
rno  Rattus norvegicus (rat)
Pathway
rno03082  ATP-dependent chromatin remodeling
rno03083  Polycomb repressive complex
rno04110  Cell cycle
rno04213  Longevity regulating pathway - multiple species
rno04330  Notch signaling pathway
rno04350  TGF-beta signaling pathway
rno04613  Neutrophil extracellular trap formation
rno04919  Thyroid hormone signaling pathway
rno05016  Huntington disease
rno05031  Amphetamine addiction
rno05034  Alcoholism
rno05165  Human papillomavirus infection
rno05169  Epstein-Barr virus infection
rno05200  Pathways in cancer
rno05202  Transcriptional misregulation in cancer
rno05203  Viral carcinogenesis
rno05206  MicroRNAs in cancer
rno05220  Chronic myeloid leukemia
Brite
KEGG Orthology (KO) [BR:rno00001]
 09120 Genetic Information Processing
  09126 Chromosome
   03082 ATP-dependent chromatin remodeling
    297893 (Hdac1)
   03083 Polycomb repressive complex
    297893 (Hdac1)
 09130 Environmental Information Processing
  09132 Signal transduction
   04330 Notch signaling pathway
    297893 (Hdac1)
   04350 TGF-beta signaling pathway
    297893 (Hdac1)
 09140 Cellular Processes
  09143 Cell growth and death
   04110 Cell cycle
    297893 (Hdac1)
 09150 Organismal Systems
  09151 Immune system
   04613 Neutrophil extracellular trap formation
    297893 (Hdac1)
  09152 Endocrine system
   04919 Thyroid hormone signaling pathway
    297893 (Hdac1)
  09149 Aging
   04213 Longevity regulating pathway - multiple species
    297893 (Hdac1)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    297893 (Hdac1)
   05202 Transcriptional misregulation in cancer
    297893 (Hdac1)
   05206 MicroRNAs in cancer
    297893 (Hdac1)
   05203 Viral carcinogenesis
    297893 (Hdac1)
  09162 Cancer: specific types
   05220 Chronic myeloid leukemia
    297893 (Hdac1)
  09172 Infectious disease: viral
   05169 Epstein-Barr virus infection
    297893 (Hdac1)
   05165 Human papillomavirus infection
    297893 (Hdac1)
  09164 Neurodegenerative disease
   05016 Huntington disease
    297893 (Hdac1)
  09165 Substance dependence
   05031 Amphetamine addiction
    297893 (Hdac1)
   05034 Alcoholism
    297893 (Hdac1)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03036 Chromosome and associated proteins [BR:rno03036]
    297893 (Hdac1)
Enzymes [BR:rno01000]
 3. Hydrolases
  3.5  Acting on carbon-nitrogen bonds, other than peptide bonds
   3.5.1  In linear amides
    3.5.1.98  histone deacetylase
     297893 (Hdac1)
Chromosome and associated proteins [BR:rno03036]
 Eukaryotic type
  Histone modification proteins
   HDACs (histone deacetylases)
    Class I HDACs
     297893 (Hdac1)
   HDAC complexes
    Sin3A-HDAC complex
     297893 (Hdac1)
    BRAF-HDAC complex
     297893 (Hdac1)
    REST complex
     297893 (Hdac1)
    SHIP complex
     297893 (Hdac1)
    MiDAC complex
     297893 (Hdac1)
   Polycomb repressive complex (PRC) and associated proteins
    Noncanonical PRC1 (PRC1.6)
     297893 (Hdac1)
  Heterochromatin formation proteins
   Other heterochromatin formation proteins
    297893 (Hdac1)
  Chromatin remodeling factors
   NuRD complex
    297893 (Hdac1)
SSDB
Motif
Pfam: Hist_deacetyl
Other DBs
NCBI-GeneID: 297893
NCBI-ProteinID: NP_001020580
RGD: 1309799
Ensembl: ENSRNOG00000009568
UniProt: Q4QQW4 A6ISJ4
Position
5:complement(147138328..147165387)
AA seq 482 aa
MAQTQGTKRKVCYYYDGDVGNYYYGQGHPMKPHRIRMTHNLLLNYGLYRKMEIYRPHKAN
AEEMTKYHSDDYIKFLRSIRPDNMSEYSKQMQRFNVGEDCPVFDGLFEFCQLSTGGSVAS
AVKLNKQQTDIAVNWAGGLHHAKKSEASGFCYVNDIVLAILELLKYHQRVLYIDIDIHHG
DGVEEAFYTTDRVMTVSFHKYGEYFPGTGDLRDIGAGKGKYYAVNYPLRDGIDDESYEAI
FKPVMSKVMEMFQPSAVVLQCGSDSLSGDRLGCFNLTIKGHAKCVEFVKSFNLPMLMLGG
GGYTIRNVARCWTYETAVALDTEIPNELPYNDYFEYFGPDFKLHISPSNMTNQNTNEYLE
KIKQRLFENLRMLPHAPGVQMQAIPEDAIPEESGDEDEEDPDKRISICSSDKRIACEEEF
SDSDEEGEGGRKNSSNFKKAKRVKTEDEKEKDPEEKKEVTEEEKTKEEKPEAKGVKEEVK
MA
NT seq 1449 nt   +upstreamnt  +downstreamnt
atggcgcagactcagggcaccaagaggaaagtctgttactactacgacggggatgttgga
aactactattatggacaagggcacccaatgaagcctcaccgaatccgaatgactcataat
ttgctgctcaactatggtctctaccgaaaaatggaaatctatcgtcctcacaaagccaac
gctgaggagatgaccaagtaccacagcgacgactacatcaagttcttgcgttctattcgc
ccagacaatatgtctgaatacagcaagcagatgcagagattcaacgtgggtgaggactgt
ccggtatttgatggcttgtttgagttctgtcagttgtccacgggtggctctgtcgcgagt
gctgtgaaactcaataagcagcagacggacatcgctgtgaactgggctgggggcctgcac
catgcgaagaagtctgaagcatccggcttctgttacgtcaatgatattgtcttggccatc
ctggaactgctaaagtatcaccagagggtgctgtatattgacattgacattcaccatggc
gatggcgtggaagaggccttctataccacagaccgggtcatgactgtgtcctttcataaa
tacggagagtacttcccaggaactggggacctacgggatattggggctggcaaaggcaag
tactacgccgttaactacccactgcgagatggcattgatgatgagtcctatgaagccatc
tttaagccagtcatgtccaaagtaatggagatgttccagcctagtgcagtggtcctacag
tgcggctcagactccctgtctggggatcggctaggttgcttcaatctgaccatcaaagga
catgccaagtgtgtggagttcgtgaagagtttcaacttgccgatgctaatgttgggagga
ggtggctataccatccgtaatgtcgctcggtgctggacttacgagacagctgtggccctg
gacacagagatccctaatgagctaccatacaatgactactttgaatactttggaccagat
ttcaagcttcacatcagcccttccaatatgactaaccagaacactaatgaatacctggag
aagatcaagcagcggctctttgagaacttgagaatgctgccccatgcccctggggtccaa
atgcaggccatcccagaggatgccatcccagaagagagcggtgatgaggatgaggaagac
cctgacaaacgaatttccatctgctcctctgacaaacgcattgcctgtgaggaggaattc
tctgattctgatgaggagggagaaggaggtcgcaagaactcttctaacttcaaaaaagcc
aaaagagtcaaaacagaagatgaaaaagaaaaagatcccgaggagaaaaaagaagtcaca
gaagaggagaaaaccaaggaggagaagccagaagccaaaggggtcaaagaagaggtcaag
atggcctga

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Ontology (3)   
   KEGG BRITE (3)   
Pathway (18)   
   KEGG PATHWAY (18)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (6)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   OC (1)   
   RGD (1)   
Protein sequence (4)   
   UniProt (2)   
   SWISS-PROT (1)   
   RefSeq(pep) (1)   
DNA sequence (11)   
   RefSeq(nuc) (1)   
   GenBank (5)   
   EMBL (5)   
Protein domain (1)   
   Pfam (1)   
All databases (45)   

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